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Malvern Instruments

 •  September 21

Written by: Matt McGann I know this sounds like the beginning of a bad joke, but in this case, it was actually the beginning of the 2017 Colorado Protein Stability Conference, held in July at Beaver Run Resort in Breckenridge, Colorado. In attendance was a range of scientists and researchers from all over the world, with one common subject in...

Malvern Instruments

 •  August 31

Written by: John Duffy GEN covers the role of MDRS in reducing the need for clinical bioequivalence endpoint studies The technique of Morphological Directed Raman Spectroscopy (MDRS) combines the capabilities of automated imaging with Raman spectroscopy, creating a powerful analytical tool that spans multiple industries. It exhibits particular...

Malvern Instruments

 •  August 22

Written by: Ulf Nobbmann Zetasizer: 21CFR? Electronic Record/Electronic Signature? Test Schedule? The Malvern Zetasizer is an extremely versatile measurement system. By far the most systems are used in academic and industry research laboratories, for example in fundamental research, drug discovery, or formulation optimization. However, a...

Malvern Instruments

 •  August 10

Written by: Severine Michel Having managed X-ray diffraction labs at previous jobs and in grad school, we know that there are a number of factors to consider when the time comes to add or replace an X-ray diffraction (XRD) system in your lab. Benchtop XRD systems may be a compact and cost-effective alternative to floor standing systems. Deciding...

Malvern Instruments

 •  August 8

Malvern Panalytical, a global leader in analytical characterization technology development, has announced a collaboration with specialist Internet of Things (IoT) company, TetraScience, to deploy IoT-enabled capabilities and connectivity for its instruments. The objective of the collaboration will be to provide access to customized dashboards, data...

Malvern Instruments

 •  August 3

Written by: Ulf Nobbmann Intralipid-Lipid emulsions Lipid emulsions are administered intravenously for a variety of purposes: To help feed patients with temporary difficulty in ingesting food orally For better transport of lipophilic drugs (fat-friendly active ingredient (API) which is not soluble in water) For controlled release of drugs (size...

Malvern Instruments

 •  July 20

Written by: Severine Michel As communicated last year, as of 1 January 2017 Malvern Instruments and PANalytical have merged their activities. Both companies are owned by parent company Spectris plc and are world leading suppliers of analytical instrumentation, PANalytical for X-ray instrumentation and software for the purpose of materials...

Malvern Instruments

 •  July 18

Written by: Ulf Nobbmann Monclonal Antibodies – or mAbs for short
Image – RCSB PDB website Since many of these mAbs require refrigeration we had used dynamic light scattering (with a Zetasizer) to show the formation of aggregates after freeze-thaw cycles (for details see application note “Effect of storage conditions on Immunoglobulin“). These...

Malvern Instruments

 •  July 4

Written by: Verna Frasca Protein Antigens and DSC This blog highlights two recent articles that focus on the use of a MicroCal Differential Scanning Calorimetry (DSC) system. Differential Scanning Calorimetry – A Method for Assessing the Thermal Stability and Conformation of Protein Antigen I.B. Duruwoju, K.M. Bhandal, J. Hu, B. Carpick, and M....

Malvern Instruments

 •  June 13

Written by: Alan Rawle I recently presented a webinar exploring the practical aspects of sieving method – the advantages and disadvantages. I compared the method to other techniques such as laser diffraction indicating the increased wealth of information that can be obtained with these more modern instrumental techniques and the common pitfalls...