Charles River Endotoxin Microbial Detection EU

Charles River Endotoxin Microbial Detection EU
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Four tips for choosing the best platform for identifying and characterizing the bugs that are lurking in your facilities It’s common for microbes to turn up in a pharmaceutical or medical device facility, and understanding the who, what, where and why is a real high-tech game of sleuthing. Yet unlike all those detective shows, where the forensic...

Charles River Laboratories International, Inc. (NYSE: CRL) today announced the expansion of its CRISPR/Cas9 service offering with the addition of a license from ERS Genomics Limited. The license, coupled with the existing license through the Broad Institute of MIT and Harvard, allows Charles River to offer custom in vivo and in vitro genome...

The FDA’s actions address the promise of innovative products and mounting concerns over stem cell clinics Last week, the Food and Drug Administration’s moved to accelerate the review of extremely complex gene therapies and cellular therapeutics, while vowing to crack down on so-called stem clinics peddling dubious products derived from a person’s...

No substitute for human brain, but robots bring the brawn Two of CRL’s safety assessment sites are using cutting-edge robot technology to take the tedium out of bench work. The facilities in Reno, Nevada and Den Bosch, The Netherlands, have successfully integrated automation into multiple bioassay workflows, freeing researchers from considerable...

The future of tissue generation may be 3D printing. Day Two of CRL’s World Congress meeting. Imagine every person on the transplant wait-list getting a new organ in seconds. Imagine if the organs could be created from the patient’s own cells, thus minimizing the risk of rejection. Imagine drug trials using artificial human tissue, and you will...

How an alternative business model helps companies retain visibility and increase speed to market but remove day-to-day struggles. The pharmaceutical and biotech industries are consistently looking for ways to bring biologics to market quickly, safely, and cost-effectively. One way has been to outsource their drug discovery and development efforts....

– Establishes Charles River as a Premier Source for CNS Contract Research Services –
WILMINGTON, Mass.--(BUSINESS WIRE)--Aug. 7, 2017-- Charles River Laboratories International, Inc. (NYSE: CRL) today announced that it has acquired Brains On-Line, a leading contract research organization (CRO) providing critical data that advances novel...

PROTAC Mediated Protein Degradation—using small molecules to manipulate our cellular machinery As a medicinal chemist I have spent half my professional life trying to re-capitulate the phenotype observed in a genetically modified “knock-out” animal using a small molecule that blocks the function of the knocked out protein. Using medicinal...

Resolution of the Microbial Identification-system should be considered when identifying QC strains. MicroPhyles Case No. 5 Someone once said, “If you don’t have time to do it right you must have time to do it over.” The ubiquitousness of Quality Control (QC) mechanisms in manufacturing processes and testing laboratories are a testament to this...

As scientists, we recognize that ours is not a static discipline. We are trained to reflect on the scientific literature so that we can codify accumulated knowledge, test new hypotheses and move forward. We are innovators. In the 1970s, “But we’ve always done it this way” was a rallying call to change how we thought about pyrogen testing and work...